??A) according to the anatomy parts classification:
??
??Type anatomy parts proportion of common histologic type central lung cancer leaf, period of bronchial above accounted for about three-quarters of squamous cell carcinoma and small cell anaplastic carcinoma peripheral lung cancer period of bronchial Richard tube the following accounts for about a quarter adenocarcinoma
??
??2) according to the histologic classification
??
??According to each model the differentiation of lung cancer and morphological characteristics, will now lung cancer is divided into two categories, namely small cell lung cancer (SCLC) and the small cell lung cancer (NSCLC), which includes squamous cell carcinoma, gland cancer, large cell carcinoma.
??
??1. Small cell lung cancer
??
??Also called small cell anaplastic carcinoma.In the lung cancer in the highest degree malignant, accounts for about 1/5 of the lung cancer l / 4 ~, patients younger age, many in 40 ~ 50 years old, with a history of smoking.Most of the bronchial originated in big, tend to submucosal tumor gro?..wth, often early hilar lymph nodes, mediastinum, infringement and blood vessels.Cancer cells to grow fast, distant metastasis early, often metastasize to the brain, liver and bone, adrenal and so on, more sensitive to radiation and chemotherapy.
??
??The cancer cells have DuoZhong form, such as lymphoid, oats sample, spindle etc, and points oat cell type, middle and complex cell type, immunohistochemical and special tumor marker, think SCLC belongs to neuroendocrine source sex tumour.
??
??2. Non-small cell lung cancer cells each installment, the treatment of similar, but different types of histology, its clinical manifestations are different.
??
??(1) squamous cell carcinoma (hereinafter referred to as squamous cell carcinoma) : in the lung cancer is the most common, accounting for about 1/2, more common in older men, and smoking for close above bronchial mucosa, tend to the lumen of growth, often cause bronchial stenosis in early, atelectasis or obstructive pneumonia, cancer tissue necrosis and form empty to occur.Squamous cell carcinoma general grew more slowly, transfer of late, surgical resection opportunity more, the 5-year survival rate is higher, but the sensitivity of radiation and chemotherapy as small cell carcinoma.
??
??A large scale cancer cells, with horns pleomorphism, tendency, intercellular Bridges see more, often with a squamous epithelial appearance arrangement.Electron microscopy see cancer cells have bridge connection between grain, ZhangLiWei wire attached.
??
??(2) adenocarcinoma: about of lung cancer l / 4, women see more, and smoking no close relationship that happens at the perimeter of the lung, small bronchial mucus glands, adenocarcinomas tend to grow, and to follow the tube alveolar walls spread, often in the formation of lung edge diameter 2 ~ 4 cra bump, adenocarcinoma, so rich blood vessels local invasion and blood did earlier, easy to transfer the pleural involvement by pleural effusion.
??
??The typical gland cancer cells, the gland sample papillary, cytoplasm, often in rich contain myxoid, electron microscopy, the cancer cells have between the cavity, connection compound and refers to the sudden shape connection.
??
??The bronchioloalveolar carcinoma of adenocarcinoma of a subtype of lung cancer, 2% ~ 5%, the younger age, and the relationship between smoking is not big, general form can be divided into a single micronodular type nodules are visible, and diffuse, a single central micronodular
??A) according to the anatomy parts classification:
??
??Type anatomy parts proportion of common histologic type central lung cancer leaf, period of bronchial above accounted for about three-quarters of squamous cell carcinoma and small cell anaplastic carcinoma peripheral lung cancer period of bronchial Richard tube the following accounts for about a quarter adenocarcinoma
??
??2) according to the histologic classification
??
??According to each model the differentiation of lung cancer and morphological characteristics, will now lung cancer is divided into two categories, namely small cell lung cancer (SCLC) and the small cell lung cancer (NSCLC), which includes squamous cell carcinoma, gland cancer, large cell carcinoma.
??
??1. Small cell lung cancer
??
??Also called small cell anaplastic carcinoma.In the lung cancer in the highest degree malignant, accounts for about 1/5 of the lung cancer l / 4 ~, patients younger age, many in 40 ~ 50 years old, with a history of smoking.Most of the bronchial originated in big, tend to submucosal tumor growth, often early hilar lymph nodes, mediastinum, infringement and blood vessels.Cancer cells to grow fast, distant metastasis early, often metastasize to the brain, liver and bone, adrenal and so on, more sensitive to radiation and chemotherapy.
??
??The cancer cells have DuoZhong form, such as lymphoid, oats sample, spindle etc, and points oat cell type, middle and complex cell type, immunohistochemical and special tumor marker, think SCLC belongs to neuroendocrine source sex tumour.
??
??2. Non-small cell lung cancer cells each installment, the treatment of similar, but different types of histology, its clinical manifestations are different.
??
??(1) squamous cell carcinoma (hereinafter referred to as squamous cell carcinoma) : in the lung cancer is the most common, accounting for about 1/2, more common in older men, and smoking for close above bronchial mucosa, tend to the lumen of growth, often cause bronchial stenosis in early, atelectasis or obstructive pneumonia, cancer tissue necrosis and form empty to occur.Squamous cell carcinoma general grew more slowly, transfer of late, surgical resection opportunity more, the 5-year survival rate is higher, but the sensitivity of radiation and chemotherapy as small cell carcinoma.
??
??A large scale cancer cells, with horns pleomorphism, tendency, intercellular Bridges see more, often with a squamous epithelial appearance arrangement.Electron microscopy see cancer cells have bridge connection between grain, ZhangLiWei wire attached.
??
??(2) adenocarcinoma: about of lung cancer l / 4, women see more, and smoking no close relationship that happens at the perimeter of the lung, small bronchial mucus glands, adenocarcinomas tend to grow, and to follow the tube alveolar walls spread, often in the formation of lung edge diameter 2 ~ 4 cra bump, adenocarcinoma, so rich blood vessels local invasion and blood did earlier, easy to transfer the pleural involvement by pleural effusion.
??
??The typical gland cancer cells, the gland sample papillary, cytoplasm, often in rich contain myxoid, electron microscopy, the cancer cells have between the cavity, connection compound and refers to the sudden shape connection.
??
??The bronchioloalveolar carcinoma of adenocarcinoma of a subtype of lung cancer, 2% ~ 5%, the younger age, and the relationship between smoking is not big, general form can be divided into a single micronodular type nodules are visible, and diffuse, a single central micronodular
??Points lesions, diffuse grow very slowly to invade and one side or both sides lung lung wild.The typical this type of cancer cells more for a well-differentiated columnar cells along the bronchi, the alveolar walls and spread on the surface, or destruction of lung, the alveolar structure within myxoid things often have deposits.
??
??(3) large cell carcinoma (large cell anaplastic carcinoma) : can happen at lung near the door or lung cancer cells surrounding, large, poorly differentiated, form a diverse solid nests, common arrangement of hemorrhagic necrosis, can be divided into two types: clear cell carcinoma: large body of the cytoplasm, a transparent shape, should with metastatic renal, from thyroid clear cell carcinoma photograph differentiate.Giant cell carcinoma: mononuclear or more nuclear giant tumor cells take more than 30%, the cancer cells diffuse distribution, large cell carcinoma small cell carcinoma of the transfer late, surgical resection bigger opportunity.
??
??3. Other bronchial glands cancer, kind of cancer.
??
??Add: the world health organization (WHO) the histologic classification recommended lung cancer
??
??(1) a squamous cell carcinoma.
??
??(2) small cell carcinoma: oat cell carcinoma;Middle cell carcinoma;Complex oat cell carcinoma.
??
??(3) adenocarcinoma: gland bubble type adenocarcinomas;Papillary adenocarcinoma;The bronchioloalveolar carcinoma;Entity with mucous cancer formation
??
??(4) large cell carcinoma;Giant cell carcinoma;Clear cell carcinoma.
??
??(5) gland squamous cell carcinoma.
??
??(6) kind of cancer.
??
??(7) the other.
Monday 29 August 2011
Lung cancer credits lung cancer pathological and classification ...
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